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Experimental and Clinical Pharmacology Laboratory

Experimental and Clinical Pharmacology Laboratory

Head of Laboratory: Lars Arendt-Nielsen, Professor (LAN)
This lab is affiliated to the Integrative Neuroscience Research Group

Aim

To perform Basic (e.g. Immunohistochemistry, Immunocytochemistry) and in vivo (e.g. Electrophysiology, Orofacial Operant Test) studies to develop suitable models and biomarkers for investigating the efficacy and safety of certain medications
To perform clinical research on medicines carried out in healthy volunteers or patients (Clinical Trials)

          

 

Main Research Areas

The studies performed by the laboratory are part of a wider context of research at the Department of Health Science and Technology (e.g. SMI collaboration with Biomedicine).

The main activities focus on:

  • Neuropharmacology (e.g. Analgesics)
  • Immunopharmacology (e.g. Anti inflammatory drugs, Anti allergic drugs)
  • Neurotoxins (e.g. Botulinum Toxin Type A)
  • Migraine Headache (Mechanisms, Novel targets)
  • Glial modulation of pain
  • miRNA in pain
  • Cancer pain
  • Pain genetics
  • Microdialysis

 

 
 
 
 
 
 
 

Key Collaborators

  • Asbjørn M. Drewes, Mech-Sense, Department of Gastroenterology, Aalborg Hospital, Denmark
  • Frederik Dagnaes-Hansen, DVM, PhD, Department of Medical Microbiology and Immunology, University of Aarhus, Denmark
  • Hans Christian Hoeck, CCBR Aalborg, Denmark
  • Flemming Bach, Neurology department, Aalborg University Hospital, Denmark
  • Ali Karshenas, Neurology department, Aalborg University Hospital, Denmark
  • Jimmi Nielsen, Aalborg Psychiatric Hospital, Denmark
  • Brian E Cairns, Faculty of Pharmaceutical Sciences, The University of British Columbia, Canada
  • John Jarrell, University of Calgary, Canada
  • Paul Rolan, School of Medical Sciences, University of Adelaide, Australia
  • Hikaru Kohase, Tokyo Medical and Dental University, Japan

Location

Fredrik Bajers Vej 7D, 3-111