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Exercise Physiology Laboratory

Exercise Physiology Laboratory

Heads of Laboratory: Jesper Franch, Associate professor (JF), and Ryan Godsk Larsen, Assistant Professor (RGL)

This lab is affiliated to the Physical Activity and Human Performance group

Aim

The aim of the laboratory is to study how the human body responds and adapts to various forms of exercise. We study the physiological responses to single bouts of exercise as well as the adaptations to training interventions tailored to improve exercise performance. To do so, we use a range of state-of-the-art techniques such as indirect calorimetry, near-infrared spectroscopy (NIRS) and magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS).

Main Research Areas

  • Training intervention for improving exercise performance:
  • Randomized, controlled studies involving high intensity interval training of trained and elite athletes
  • Influence of dietary nitrate supplementation on exercise performance: Randomized, controlled studies examining the effects of beet root juice on time trial performance, muscle oxygenation, kinetics of oxygen uptake, exercise economy and microvascular function
  • Effects of hypoxia (simulated altitude) on exercise performance: Randomized, controlled studies examining the effects of hypoxia (compared with normoxia) on time trial performance, muscle oxygenation, kinetics of oxygen uptake and microvascular function
  • Developing methods to quantify energy expenditure during physical activity:
    - Validating a novel thermal imaging method to quantity energy expenditure during human locomotion
  • Effects of eccentric exercise on vascular function:
    Using MR blood oxygen level dependent (BOLD) imaging and Doppler ultrasound to assess effects of muscle damage on microvascular function in humans
  • Characterization of muscle metabolism and mitochondrial function: Using 31P to assess in vivo mitochondrial function and muscle energetics during muscle contractions

Key Collaborators

  • Norwegian School of Sport Sciences (Jørgen Jensen)
  • University of Aarhus, Department of Public Health (Kristian Overgaard, Klavs Madsen)
  • University of Copenhagen, Department of Nutrition, Exercise and Sports (Ylva Hellsten)
  • Aalborg University Hospital, Department of Radiology (Jens Brøndum Frøkjær)
  • Aalborg University, Department of Architecture, Design and Media Technology (Thomas Moeslund)